Dynamic-contrast-enhanced-MRI with extravasating contrast reagent: Rat cerebral glioma blood volume determination
نویسندگان
چکیده
منابع مشابه
DCE-MRI Rat Cerebral Glioma Blood Volume Determination with Extravasating CR
INTRODUCTION The accurate determination of tumor blood volume fraction (vb) is a highly desired imaging biometric goal. It is commonly thought that this is difficult, if not impossible, for Dynamic-Contrast-Enhanced (DCE) MRI because angiogenic malignant tumor vessels allow fast contrast reagent (CR) extravasation. Most DCE-MRI pharmacokinetic models modify derivations for directly-detected tra...
متن کاملComparison of cerebral blood volume and vascular permeability from dynamic susceptibility contrast-enhanced perfusion MR imaging with glioma grade.
BACKGROUND AND PURPOSE Relative cerebral blood volume (rCBV) and vascular permeability (K(trans)) permit in vivo assessment of glioma microvasculature. We assessed the associations between rCBV and K(trans) derived from dynamic, susceptibility-weighted, contrast-enhanced (DSC) MR imaging and tumor grade and between rCBV and K(trans). METHODS Seventy-three patients with primary gliomas underwe...
متن کاملPreoperative prognostic value of dynamic contrast-enhanced MRI-derived contrast transfer coefficient and plasma volume in patients with cerebral gliomas.
BACKGROUND AND PURPOSE The prognostic value of dynamic contrast-enhanced MR imaging-derived plasma volume obtained in tumor and the contrast transfer coefficient has not been well-established in patients with gliomas. We determined whether plasma volume and contrast transfer coefficient in tumor correlated with survival in patients with gliomas in addition to other factors such as age, type of ...
متن کاملTracer delay correction of cerebral blood flow with dynamic susceptibility contrast-enhanced MRI.
Cerebral blood flow (CBF) and vascular mean transit time (MTT) can be determined by dynamic susceptibility contrast-enhanced magnetic resonance imaging and deconvolution with an arterial input function. However, deconvolution by a singular value decomposition (SVD) method is sensitive to the tracer delay that often occurs in patients with cerebrovascular disease. We investigated the effect of t...
متن کاملIntraoperative Cerebral Glioma Characterization with Contrast Enhanced Ultrasound
BACKGROUND Contrast enhanced ultrasound (CEUS) is a dynamic and continuous modality providing real-time view of vascularization and flow distribution patterns of different organs and tumors. Nevertheless its intraoperative use for brain tumors visualization has been performed few times, and a thorough characterization of cerebral glioma had never been performed before. AIM To perform the firs...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Magnetic Resonance
سال: 2010
ISSN: 1090-7807
DOI: 10.1016/j.jmr.2010.07.004